大学関係・学生の皆様へ

研究業績

研究業績一覧

平成30年(2018年)

  1. Shoji N, Arakaki Y, Nakamoto K, Yamamoto T, Kuwayama Y; Collaborative Bleb-related Infection Incidence and Treatment Study Group. Efficacy of predetermined therapeutic measures against bleb-related infection in the collaborative bleb-related infection incidence and treatment study. Acta Ophthalmologica 96: e229-e236, 2018.
  2. Haga A, Kawaji T, Ideta R, Inomata Y, Tanihara H. Treat-and-extend versus every-other-month regimens with aflibercept in age-related macular degeneration. Acta ophthalmologica 96: e393-e398,2018.
  3. Iraha S, Tu HY, Yamasaki S, Kagawa T, Goto M, Takahashi R, Watanabe T, Sugita S, Yonemura S, Sunagawa GA, Matsuyama T, Fujii M, Kuwahara A, Kishino A, Koide N, Eiraku M, Tanihara H, Takahashi M, Mandai M. Establishment of immunodeficient retinal degeneration model mice and functional maturation of human ESC-derived retinal sheets after transplantation. Stem Cell Reports 10: 1059-1074, 2018.
  4. Tsutsumi-Kuroda U, Inoue T, Futakuchi A, Shobayashi K, Takahashi E, Kojima S, Inoue-Mochita M, Fujimoto T, Tanihara H. Decreased MCP-1/CCR2 axis-mediated chemotactic effect of conjunctival fibroblasts after transdifferentiation into myofibroblasts. Experimental Eye Research 170: 76080, 2018.
  5. Nakashima KI, Iwao K, Inoue T, Haga A, Tsutsumi T, Mochita MI, Fujimoto T, Tanihara H. Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cells. Experimental Eye Research 170: 160-168, 2018.
  6. Yamagishi-Kimura R, Honjo M, Komizo T, Ono T, Yagi A, Lee J, Miyata K, Fujimoto T, Inoue T, Tanihara H, Nishida J, Uchida T, Araki Y, Aihara M. Interaction between pilocarpine and ripasudil on intraocular pressure, pupil diameter, and the aqueous-outflow pathway. Investigative Ophthalmology & Visual Science 59: 1844-1854, 2018.
  7. Inoue-Mochita M, Inoue T, Kojima S, Futakuchi A, Fujimoto T, Sato-Ohira S, Tsutsumi U, Tanihara H. Interleukin-6-mediated trans-signaling inhibits transforming growth factor-β signaling in trabecular meshwork cells. Journal of Biological Chemistry 293:10975-10984, 2018.
  8. Futakuchi A, Inoue T, Wei FY, Inoue-Mochita M, Fujimoto T, Tomizawa K, Tanihara H. YAP/TAZ Are Essential for TGF-β2-Mediated Conjunctival Fibrosis. Investigative Ophthalmology & Visual Science 59:3069-3078, 2018.

平成29年(2017年)

  1. Matsumura R, Inoue T, Matsumura A, Tanihara H. Efficacy of ripasudil as a second-line medication in addition to a prostaglandin analog in patients with exfoliation glaucoma: A pilot study. Clinical Drug Investigation, 37: 535-539, 2017.
  2. Futakuchi A, Inoue T, Fujimoto T, Kuroda U, Inoue-Mochita M, Takahashi E, Ohira S, Tanihara H. Molecular mechamisms underlying the filtration bleb-maintaining effects of suberoylanilide hydroxamic acid (SAHA). Investigative Ophthalmology & Visual Science 58: 2421-2429, 2017.
  3. Fujimoto T, Inoue T, Ohira S, Awai-Kasaoka N, Kameda T, Inoue-Mochita M, Tanihara H. Inhibition of Rho kinase induces antioxidative molecules and suppresses reactive oxidative species in trabecular meshwork cells. Journal of Ophthalmology, 7598140, 2017.
  4. Araie M, Iwase A, Sugiyama K, Nakazawa T, Tomita G, Hangai M, Yanagi Y, Murata H, Tanihara H, Burgoyne CF, Chauhan BC. Determinants and characteristics of Bruch's membrane opening and Bruch's membrane opening-minimum rim width in a normal Japanese population. Investigative Ophthalmology & Visual Science 58: 4106-4113, 2017.
  5. Watanabe-Kitamura F, Inoue T, Kojima S, Nakashima KI, Fukushima A, Tanihara H. Prospective 3D investigation of bleb wall after trabeculectomy using nterior-segment OCT. Journal of Ophthalmology 2017: 8261364, 2017.
  6. Inoue T, Tanihara H. Ripasudil hydrochloride hydrate: targeting Rho kinase in the treatment of glaucoma. Expert Opinion on Pharmacotherapy 14:1-5, 2017. Review.

平成28年(2016年)

  1. Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Fukushima A, Suganami H, Araie M for the K-115 Clinical Study Group. One-year clinical evaluation of 0.4% ripasudil (K-115) in patients with open-angle glaucoma and ocular hypertension. Acta Ophthalmologica 94: e26-34, 2016.
  2. Matsumura R, Inoue T, TaniharaH. Bleb-like findings caused by idiopathic scleral thinning in an eye with absolute glaucoma. Journal of Glaucoma, 25: e288-290, 2016.
  3. Kawaji T, Sato T, Tanihara H. Suturelessintrascleral intraocular lens fixation with lamellar dissection of scleral tunnel.strong Clinical Ophthalmology 10: 227-231, 2016.
  4. Kaneko Y, Ohta M, Inoue T, Mizuno K, Isobe T, Tanabe S, Tanihara H. Effects of K-115 (ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells. Scientific Reports 6: 19640, 2016.
  5. Ohira S, Inoue T, Iwao K, Takahashi E, Tanihara H. Factors influencing aqueous proinflammatory cytokines and growth factors in uveitic glaucoma. PLoS One 11: e0147080, 2016.
  6. Nishisako M, Meguro A, Nomura E, Yamane T, Takeuchi M, Ota M, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Chin S, Ohno S, Inoko H, Mizuki N.SLC1A1 gene variants and normal tension glaucoma: An association study. Ophthalmic Genetics, in press. (Jan 15: 1-7, 2016. [Epub ahead of print])
  7. Takahashi E, Fukushima A, Haga A, Inomata Y, Ito Y, Fukushima M, Tanihara H. Effects of mechanical stress and vitreous samples in retinal pigment epithelial cells. Biochemical and Biophysical Research Communications 470: 569-574, 2016.
  8. Kojima S, Inoue T, Kikuta J, Furuya M, Koga A, Fujimoto T, Ueta M, Kinoshita S, Ishii M, Tanihara H. Visualization of intravital immune cell dtynamics after conjunctival surgery using multiphoton microscopy. Investigative Ophthalmology & Visual Science 57: 1207-1212, 2016.
  9. Fujimoto T, Inoue T, Inoue-Mochita M, Tanihara H. Live cell imaging of actin dynamics in dexamethasone-treated porcine trabecular meshwork cells. Experimental Eye Research 145: 393-400, 2016.
  10. Nishizawa A, Inoue T, Ohira S, Takahashi E, Saruwatari J, Iwao K, Tanihara H. The influence of phacoemulsification on surgical outcomes of trabeculectomy with mitomycin-C for uveitic glaucoma. PLoS One 11: e0151947, 2016.
  11. Haga A, Takahashi E, Inomata Y, Kawahara K, Tanihara H. Differentiated expression patterns and phagocytic activities of type 1 and 2 microglia. Investigative Ophthalmology & Visual Science, in press,

平成27年(2015年)

  1. Kojima S, Inoue T, Nakashima K, Fukushima A, Tanihara H. Filtering blebs using 3-dimensional anterior-segment optical coherence tomography: a prospective investigation. JAMA Ophthalmol133: 148-156, 2015.
  2. Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Suganami H, Araie M for the K-115 Clinical Study Group. Intra-ocular pressure-lowering effects of a Rho kinase inhibitor, ripasudil (K-115), over 24 hours in primary open-angle glaucoma and ocular hypertension: a randomized, open-label, crossover study. Acta Ophthalmol 93: e254-269, 2015.
  3. Tasaki M, Ueda M, Matsumoto K, Kawaji T, Misumi Y, Eiki D, Suenaga G, Obayashi K, Yamashita T, Tanihara H, Ando Y. Clinico-histopathological and biochemical analyses of corneal amyloidosis in gelatinous drop-like corneal dystrophy. Amyloid 22: 67-69, 2015.
  4. Nakashima K, Inoue T, Fukushima A, Hirakawa S, Kojima S, Tanihara H. Evaluation of filtering blebs exhibiting transconjunctival oozing using anterior segment optical coherence tomography. Graefe’s Arch Clin Exp Ophthalmol 253: 439-445, 2015.
  5. Inoue T, Tanihara H, Tokushige H, Araie M. Efficacy and safety of SNJ-1656 in primary open-angle glaucoma or ocular hypertension. Acta Ophthalmol 93: e393-395, 2015.
  6. Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Suganami H, Araie M for the K-115 Clinical Study Group. Additive intraocular pressure-lowering effects of the Rho kinase inhibitor, ripasudil (K-115), combined with timolol or latanoprost: a report of 2 randomized clinical trials. JAMA Ophthalmol 133: 755-761, 2015.
  7. Inoue-Mochita M, Inoue T, Fujimoto T, Kameda T, Awai-Kasaoka N, Ohtsu N, Kimoto K, Tanihara H. p38 MAP kinase inhibitor suppresses transforming growth factor-β2-induced type 1 collagen production in trabecular meshwork cells. PLOS ONE 10: e0120774, 2015.
  8. Takahashi E, Haga A, Tanihara H. Merlin regulates epithelial-to-mesenchymal transition of ARPE-19 cells via TAK1-p38MAPK-mediated activation. Invest Ophthalmol Vis Sci 56: 2449-2458, 2015.
  9. Ohira S, Inoue T, Shobayashi K, Iwao K, Fukushima M, Tanihara H. Simultaneous increase in multiple proinflammatory cytokines in the aqueous humor in neovascular glaucoma with and without intravitreal bevacizumab injection. Invest Ophthalmol Vis Sci 56: 3541-3548. 2015.
  10. Cho HK, Kojima S, Inoue T, Fukushima A, Kee C, Tanihara H. Effect of laser suture lysis on filtration openings: a prospective three-dimensional anterior segment optical coherence tomography study. Eye 29: 1220-1225, 2015.
  11. Shobayashi K, Inoue T, Kawai M, Iwao K, Ohira S, Kojima S, Kuroda U, Nakashima K, Tanihara H. Postoperative changes in aqueous monocyte chemotactic protein-1 levels and bleb morphology after trabeculectomy vs. Ex-PRESS shunt surgery. PLOS ONE 10: e0139751, 2015.
  12. Takihara Y, Inatani M, Eto K, Inoue T, Kreymerman A, Miyake S, Ueno S, Nagaya M, Nakanishi A, Iwao K, Takamura Y, Sakamoto H, Satoh K, Kndo M, Sakamoto T, Goldberg JL, Nabekura J, Tanihara H. In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS. Proc Natl Acad Sci USA 112: 10515-10520, 2015.

平成26年(2014年)

  1. Takihara Y, Inatani M, Ogata-Iwao M, Kawai M, Inoue T, Iwao K, Tanihara H. Trabeculectomy for open-angle glaucoma in phakic eyes vs in pseudophakic eyes after phacoemulsification: a prospective clinical cohort study. JAMA Ophthalmol 132:69-76, 2014.
  2. Iwao K, Inatani M, Seto T, Takihara Y, Ogata-Iwao M, Okinami S, Tanihara H. Long-term outcomes and prognostic factors for trabeculectomy with mitomycin C in eyes with uveitic glaucoma: a retrospective cohort study. J Glaucoma 23:88-94, 2014.
  3. Takahashi E, Inoue T, Fujimoto T, Kojima S, Tanihara H. Epithelial mesenchymal transition-like phenomenon in trabecular meshwork cells. Exp Eye Res 118:72-9, 2014.
  4. Kawaji T, Inoue T, Hara R, Eiki D, Ando Y, Tanihara H. Long-term Outcomes and Complications of Trabeculectomy for Secondary Glaucoma in Patients with Familial Amyloidotic Polyneuropathy. PLOS ONE 9:e96324, 2014.
  5. Inoue T, Kawaji T, Tanihara H. Monocyte chemotactic protein-1 level in the aqueous humor as a prognostic factor for the outcome of trabeculectomy. Clin Experiment Ophthalmol 42:334-41, 2014.
  6. Bizen N, Inoue T, Shimizu T, Tabu K, Kagawa T, Taga T. A growth-promoting signaling component cyclin D1 in neural stem cells has anti-astrogliogenic function to execute self-renewal. Stem Cells 32:1602-15, 2014.
  7. Kojima S, Inoue T, Kawaji T, Tanihara H. Filtration bleb revision guided by three-dimensional anterior segment optical coherence tomography. J Glaucoma 23:312-5, 2014.
  8. Kojima S, Inatani M, Shobayashi K, Haga, A, Inoue T, Tanihara H. Risk factors for hyphema after trabeculectomy with mitomycin C. J Glaucoma 23:307-11, 2014.
  9. Kojima S, Inoue T, Kawaji T, Tanihara H. Tear fluid signs associated with filtration blebs as demonstrated by three-dimensional anterior segment optical coherence tomography. Clin Ophthalmol 8:767-72, 2014.
  10. Kuroda U, Inoue T, Awai-Kasaoka N, Shobayashi K, Kojima S, Tanihara H. Fornix-based vs limbal-based conjunctival flaps in trabeculectomy with mitomycin C in high-risk patients. Clin Ophthalmol 8:949-54, 2014.
  11. Yamamoto T, Sawada A, Mayama C, Araie M, Ohkubo S, Sugiyama K, Kuwayama Y, The Collaborative Bleb-related Infection Incidence and Treatment Study Group: The 5-year incidence of bleb-related infection and its risk factors after filtering surgeries with adjunctive mitomycin C: CBIITS 2. Ophthalmology 121:1001-6, 2014.
  12. Kawaji T, Inoue T, Matsumura R, Kuroda U, Nakashima K and Tanihara H. Trabeculectomy Bleb Assessment via Three-dimensional Anterior Segment Optical Coherence Tomography. JSM Ophthalmology 2:1020, 2014.
  13. Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Araie M for the K-115 Clinical Study Group. Intraocular pressure-lowering effects of a Rho kinase inhibitor, ripasudil (K-115), over 24 hours in primary open-angle glaucoma and ocular hypertension - a randomized, open-label, crossover study -. Acta Ophthalmologica., 2014 Dec 9. doi: 10.1111/aos.12599. [Epub ahead of print]

平成25年(2013年)

  1. Inoue T, Tanihara H. ROCK inhibitors: a novel approach to glaucoma therapy. Prog Retin Eye Res 37:1-12, 2013.
  2. Awai-Kasaoka N, Inoue T, Inatani M, Takihara Y, Ogata-Iwao M, Tanihara H. Study on prognostic factor in trabeculectomy with mitomycin C having history of previous glaucoma surgery. Jpn J Ophthalmol 57:514-9, 2013.
  3. Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Araie M for the K-115 Clinical Study Group. Phase 2 Randomized Clinical study of a Rho kinase inhibitor, K-115, in primary open-angle glaucoma and ocular hypertension. Am J Ophthalmol 156:731-736, 2013.
  4. Inoue T, Kawaji T, Tanihara H. Elevated levels of multiple biomarkers of Alzheimer’s disease in the aqueous humor of eyes with open-angle glaucoma. Invest Ophthalmol Vis Sci 54:5353-5358, 2013.
  5. Yamamoto T, Kuwayama Y, Nomura E, Tanihara H, Mori K; Study Group for the Japan Glaucoma Society Survey of Bleb-related Infection. Changes in visual acuity and intra-ocular pressure following bleb-related infection: the Japan Glaucoma Society Survey of Bleb-related Infection Report 2. Acta Ophthalmol 91:e420-426, 2013.
  6. Tanihara H, Inoue T, Yamamoto T, Abe H, Kuwayama Y, Araie M for the K-115 Clinical Study Group. Phase 1 clinical trials of a selective Rho kinase inhibitor, K-115. JAMA Ophthalmol 131:1288-1295, 2013.
  7. Goto A, Inatani M, Inoue T, Awai-Kasaoka N, Takihara Y, Ito Y, Fukushima M, Tanihara H. Frequency and risk factors for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy. J Glaucoma 22:572-6, 2013.
  8. Kameda T, Inoue T, Inatani M, Tanihara H; Japanese Phaco-Goniosynechialysis Multicenter Study Group. Long-term efficacy of goniosynechialysis combined with phacoemulsification for primary angle closure. Graefes Arch Clin Exp Ophthalmol 251:825-830, 2013
  9. Ogata-Iwao M, Inatani M, Takihara Y, Inoue T, Iwao K, Tanihara H. A prospective comparison between trabeculectomy with mitomycin C and phacotrabeculectomy with mitomycin C. Acta Ophthalmol 91:e500-501, 2013.
  10. Awai-Kasaoka N, Inoue T, Kameda T, Fujimoto T, Inoue-Mochita M, Tanihara H. Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability. Mol Vis 19:1332-1340, 2013.
  11. Haga A, Inatani M, Shobayashi K, Kojima S, Inoue T, Tanihara H. Risk factors for choroidal detachment after trabeculectomy with mitomycin C. Clin Ophthalmol 7:1417-1421, 2013.
  12. Yamamoto T, Kuwayama Y, Kano K, Sawada A, Shojji N, the Study Group for the Japan Glaucoma Society Survey of Bleb-related Infection. Clinical features of bleb-related infection: A 5-year survey in Japan. Acta Ophthalmol 91:619-624, 2013.
  13. Arnold JJ, Hansen MS, Gorman GS, Inoue T, Rao V, Spellen S, Hunsinger RN, Chapleau CA, Posso-Miller L, Stamer WD, Challa P. The Effect of Rho-Associated Kinase (ROCK) Inhibition on the Ocular Penetration of Timolol Maleate. Invest Ophthalmol Vis Sci 54:1118-1126, 2013.
  14. Kato T, Meguro A, Nomura E, Uemoto R, Nomura N, Ota M, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Chin S, Ohno S, Inoko H, Mizuki N. Association study of genetic variants on chromosome 7q31 with susceptibility to normal tension glaucoma in a Japanese population. Eye 27:979-983, 2013.
  15. Iwao K, Goldberg JL. Therapeutics Update: Early testing of CNTF for glaucoma. Glaucoma Today May/June: 56-57, 2013.

平成24年(2012年)

  1. Inoue T, Matsumura R, Kuroda U, Nakanishi K, Kawaji T, Tanihara H. Precise identification of filtration openings on the scleral flap by three-dimensional anterior segment optical coherence tomography. Invest Ophthalmol Vis Sci. 53: 8288-8294, 2012.
  2. Hayashi H, Eguchi Y, Fukuchi-Nakaishi Y, Takeya M, Nakagata N, Tanaka K, Vance JE, Tanihara H. A potential neuroprotective role of apolipoprotein E-containing lipoproteins through low density lipoprotein receptor-related protein 1 in normal tension glaucoma. J Biol Chem, 287: 25395-406, 2012.
  3. Awai-Kasaoka N, Inoue T, Takihara Y, Kawaguchi A, Inatani M, Ogata-Iwao M, Tanihara H. Impact of phacoemulsification on failure of trabeculectomy with mitomycin C. J Cataract Refract Surg. 38: 419-24, 2012
  4. Kameda T, Inoue T, Inatani M, Fujimoto T, Honjo M, Kasaoka N, Inoue-Mochita M, Yoshimura N, Tanihara H. The effect of Rho-associated protein kinase inhibitor on monkey Schlemm’s canal endothelial cells. Invest Ophthalmol Vis Sci. 53:3092-103, 2012.
  5. Inoue T, Kawaji T, Inatani M, Kameda T, Yoshimura N, Tanihara H. Simultaneous increases in multiple proinflammatory cytokines in the aqueous humor of pseudophakic glaucomatous eyes. J Cataract Refract Surg, 38: 1389-97, 2012.
  6. Inoue T, Inatani M, Takihara Y, Awai-Kasaoka N, Ogata-Iwao M, Tanihara H. Prognostic risk factors for failure of trabeculectomy with mitomycin C after vitrectomy. Jpn J Ophthalmol, 56: 464-9, 2012.
  7. Fujimoto T, Inoue T, Kameda T, Kasaoka N, Inoue-Mochita M, Tsuboi N, Tanihara H. Involvement of RhoA/Rho-Associated Kinase Signal Transduction Pathway in Dexamethasone-induced Alterations in Aqueous Outflow. Invest Ophthalmol Vis Sci, 53: 7097-108, 2012.
  8. Tsuboi N, Inoue T, Kawai M, Inoue-Mochita M, Fujimoto T, Awai-Kasaoka N, Yoshida A, Tanihara H. The Effect of Monocyte Chemoattractant Protein-1/CC Chemokine Ligand 2 on Aqueous Humor Outflow Facility. Invest Ophthalmol Vis Sci. 53: 6702-7, 2012.
  9. Kawai M, Inoue T, Tsuboi N, Matsukawa A, Yoshida A, Tanihara H. Elevated levels of monocyte chemoattractant protein-1 in the aqueous humor after phacoemulsification. Invest Ophthalmol Vis Sci. 53: 7951-7960, 2012.
  10. Field MG, Comer GM, Kawaji T, Petty HR, Elner VM. Noninvasive Imaging of Mitochondrial Dysfunction in Dry Age-Related Macular Degeneration. Ophthalmic Surg Lasers Imaging. 19:1-8, 2012.
  11. Hisatomi T, Nakao S, Murakami Y, Noda K, Nakazawa T, Notomi S, Connolly E, She H, Almulki L, Ito Y, Vavvas DG, Ishibashi T, Miller JW. The regulatory roles of apoptosis-inducing factor in the formation and regression processes of ocular neovascularization. Am J Pathol. 181:53-61, 2012.
  12. Yamashita S, Uchida Y, Kojima S, Sakaguchi H, Kimura E, Maeda Y, Uchino M. Heatstroke in patients with Parkinson’s disease. Neurol Sci, 33: 685-7, 2012.

平成23年(2011年)

  1. Takihara Y, Inatani M, Kawaji T, Fukushima M, Iwao K, Iwao M, Tanihara H. Combined intravitreal bevacizumab and trabeculectomy with mitomycin C versus trabeculectomy with mitomycin C alone for neovascular glaucoma. J Glaucoma 20:196-201, 2011.
  2. Takihara Y, Inatani M, Seto T, Iwao K, Iwao M, Inoue T, Kasaoka N, Murakami A, Futa R, Tanihara H. Trabeculectomy with mitomycin C for open-angle glaucoma in phakic eyes vs pseudophakic eyes after phacoemulsification. Arch Ophthalmol 129:152-7, 2011.
  3. Takihara Y, Inatani M, Hayashi H, Adachi N, Iwao K, Inoue T, Iwao M, Tanihara H. Dynamic imaging of axonal transport in living retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci 52:3039-45, 2011.
  4. Iwao K, Inatani M, Tanihara H on behalf of the Japanese Steroid-Induced Glaucoma Multicenter Study Group. Success rates of trabeculotomy for steroid-induced glaucoma: a comparative, multicenter, retrospective, cohort study. Am J Ophthalmol 151:1047-56, 2011.
  5. Kawaji T, Elner VM, Yang DR, Clark A, Petty HR. Ischemia-induced nitrotyrosine formation and nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase in human retinal pigment epithelium in vivo. Redox Report 16:24-6, 2011.
  6. Yamamoto T, Kuwayama Y and The Collaborative Bleb-related Infection Incidence and Treatment Study Group. Interim clinical outcomes in the collaborative bleb-related infection incidence and treatment study. Ophthalmology 118:453-8, 2011.
  7. Yasumura R, Meguro A, Ota M, Nomura E, Uemoto R, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Investigation of the association between SLC1A3 gene polymorphisms and normal tension glaucoma. Mol Vis 17:792-6, 2011.
  8. Ohya Y, Okamoto S, Tasaki M, Ueda M, Jono H, Obayashi K, Takeda K, Okajima H, Asonuma K, Hara R, Tanihara H, Ando Y, Inomata Y. Manifestations of transthyretin-related familial amyloidotic polyneuropathy: long-term follow-up of Japanese patients after liver transplantation. Surg Today 41:1211-8, 2011.
  9. Ogata-Iwao M, Inatani M, Iwao K, Takihara Y, Nakaishi-Fukuchi Y, Irie F, Sato S, Furukawa T, Yamaguchi Y, Tanihara H. Heparan Sulfate Regulates Intraretinal Axon Pathfinding by Retinal Ganglion Cells. Invest Ophthalmol Vis Sci 52: 6671-9, 2011.
  10. Tokushige H, Takayama Y, Waki M, Tanihara H. Effects of Y-39983, a selective Rho-associated protein kinase Inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats. Curr Eye Res 36: 964-970, 2011.

平成22年(2010年)

  1. Iwao K, Inatani M, Ogata-Iwao M, Yamaguchi Y, Okinami S, Tanihara H. Heparan sulfate deficiency in periocular mesenchyme causes microphthalmia and ciliary body dysgenesis. Exp Eye Res 90:81-8, 2010.
  2. Takahashi E, Nagano O, Ishimoto T, Yae T, Suzuki Y, Shinoda T, Nakamura S, Niwa S, Ikeda S, Koga H, Tanihara H, Saya H. TNF-{alpha} regulates TGF-{beta}-dependent epithelial-mesenchymal transition by promoting hyaluronan-CD44-Moesin interaction. J Biol Chem 285:4060-73, 2010.
  3. Inoue T, Pattabiraman PP, Epstein DL, Vasantha Rao P. Effects of chemical inhibition of N-WASP, a critical regulator of actin polymerization on aqueous humor outflow through the conventional pathway. Exp Eye Res 90:360-7, 2010.
  4. Koga T, Shen X, Park JS, Qiu Y, Park BC, Shyam R, Yue BY. Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth. Am J Pathol 176:343-52, 2010.
  5. Hara R, Kawaji T, Ando E, Ohya Y, Ando Y, Tanihara H. Impact of Liver Transplantation on Transthyretin-related Ocular Amyloidosis in Japanese Patients. Arch Ophthalmol 128:206-10, 2010.
  6. Kawaji T, Ando Y, Hara R, Tanihara H. Novel therapy for transthyretin-related ocular amyloidosis: A pilot study of retinal laser photocoagulation. Ophthalmology 117:552-5, 2010.
  7. Murakami K, Meguro A, Ota M, Shiota T, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma. Mol Vis 17;16:462-6, 2010.
  8. Techasen A, Loilome W, Namwat N, Takahashi E, Sugihara E, Puapairoj A, Miwa M, Saya H, Yongvanit P. Myristoylated alanine-rich C kinase substrate phosphorylation promotes cholangiocarcinoma cell migration and metastasis via the protein kinase C-dependent pathway. Cancer Sci 101:658-65, 2010.
  9. Hara R, Kawaji T, Inomata Y, Tahara J, Sagara N, Fukushima M, Tanihara H. Photodynamic therapy alone versus combined with intravitreal bevacizumab for neovascular age-related macular degeneration without polypoidal choroidal vasculopathy in Japanese patients. Graefes Arch Clin Exp Ophthalmol 248:931-6, 2010.
  10. Inoue T, Kagawa T, Inoue-Mochita M, Isono K, Ohtsu N, Nobuhisa I, Fukushima M, Tanihara H, Taga T. Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis. FEBS Lett 584:3233-8, 2010.
  11. Petty HR, Elner VM, Kawaji T, Clark A, Thompson D, Yang DR. A facile method for immunofluorescence microscopy of highly autofluorescent human retinal sections using nanoparticles with large Stokes shifts. J Neurosci Methods 191:222-6, 2010.
  12. Hara R, Inomata Y, Kawaji T, Sagara N, Inatani M, Fukushima M, Tanihara H. Suppression of Choroidal Neovascularization by N-acetyl-cysteine in Mice. Curr Eye Res 35:1012-20, 2010.
  13. Kawaji T, Ando Y, Ando E, Sandgren O, Suhr OB, Tanihara H. Transthyretin-related vitreous amyloidosis in different endemic areas. Amyloid 17:105-8, 2010.
  14. Suzuki M, Meguro A, Ota M, Nomura E, Kato T, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma. Mol Vis 16:1874-9, 2010.
  15. The NTG Genetic Study Group of Japanese Glaucoma Society. Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility. Ophthalmology 117:1331-8, 2010.
  16. Inoue T, Pecen P, Maddala R, Skiba NP, Pattabiraman PP, Epstein DL, Rao PV. Characterization of Cytoskeletons Enriched Protein Fraction of the Trabecular Meshwork and Ciliary Muscle Cells. Invest Ophthalmol Vis Sci 51:6461-71, 2010.
  17. Yoshinaga Y, Kagawa T, Shimizu T, Inoue T, Takada S, Kuratsu JI, Taga T. Wnt3a Promotes Hippocampal Neurogenesis by Shortening Cell Cycle Duration of Neural Progenitor Cells. Cell Mol Neurobiol 30:1049-58, 2010.

平成21年(2009年)

  1. Iwao K, Inatani M, Matsumoto Y, Ogata-Iwao M, Takihara Y, Irie F, Yamaguchi Y, Okinami S, Tanihara H. Heparan sulfate deficiency leads to Peters' anomaly in mice by disturbing neural crest TGFbeta2 signaling. J Clin Invest 119:1997-2008, 2009.
  2. Takihara Y, Inatani M, Fukuhima M, Iwao K, Tanihara H. Trabeculectomy with mitomycin C for neovascular glaucoma: prognostic factors for surgical failure. Am J Ophthalmol 147:912-8, 2009.
  3. Iwao K, Inatani M, Ogata-Iwao M, Takihara Y, Tanihara H. Restricted post-trabeculectomy bleb formation by conjunctival scarring. Graefes Arch Clin Exp Ophthalmol 247:1095-101, 2009.
  4. Inomata Y, Fukushima M, Hara R, Takahashi E, Honjo M, Koga T, Kawaji T, Satoh H, Takeya M, Sawamura T, Tanihara H. Suppression of choroidal neovascularization in lectin-like oxidized low-density lipoprotein receptor type 1-deficient mice. Invest Ophthalmol Vis Sci 50:3970-6, 2009.
  5. Inoue-Mochita M, Inoue T, Epstein DL, Blumer KJ, Rao PV. RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival. Mol Vis 15:495-504, 2009.
  6. Kamio M, Meguro A, Ota M, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Investigation of the association between the GLC3A locus and normal tension glaucoma in Japanese patients by microsatellite analysis. Clin Ophthalmol 3: 183-188, 2009.
  7. Nakamura K, Ota M, Meguro A, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Association of microsatellite polymorphisms of the GPDS1 locus with normal tension glaucoma in the Japanese population. Clin Ophthalmol 3:307-12, 2009.
  8. Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, Urano T, Zhu HJ, Tsukano H, Tazume H, Kaikita K, Miyashita K, Iwawaki T, Shimabukuro M, Sakaguchi K, Ito T, Nakagata N, Yamada T, Katagiri H, Kasuga M, Ando Y, Ogawa H, Mochizuki N, Itoh H, Suda T, Oike Y. Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metab 10:178-88, 2009.
  9. Inumaru J*, Nagano O*, Takahashi E, Ishimoto T, Nakamura S, Suzuki Y, Niwa S, Umezawa K, Tanihara H and Saya H: Molecular mechanisms regulating dissociation of cell-cell junction of epithelial cells by oxidative stress. Genes Cells 14:703-16, 2009.
  10. Mochimaru H, Takahashi E, Tsukamoto N, Miyazaki J, Yaguchi T, Koto T, Kurihara T, Noda K, Ozawa Y, Ishimoto T, Kawakami Y, Tanihara H, Saya H, Ishida S, Tsubota K. Involvement of Hyaluronan and Its Receptor CD44 with Choroidal Neovascularization. Invest Ophthalmol Vis Sci 50:4410-5, 2009.
  11. Sagara N, Kawaji T, Koshiyama Y, Inomata Y, Fukushima M, Tanihara H. Macular hole formation after macular hemorrhage associated with rupture of retinal arterial macroaneurysm. Br J Ophthalmol 93:1337-40, 2009.
  12. Fukushima M, Setoguchi T, Komiya S, Tanihara H, Taga T. Retinal astrocyte differentiation mediated by leukemia inhibitory factor in cooperation with bone morphogenetic protein 2. Int J Dev Neurosci 27:685-90, 2009.
  13. Nakamura J, Meguro A, Ota M, Nomura E, Nishide T, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N. Association of toll-like receptor 2 gene polymorphisms with normal tension glaucoma. Mol Vis 15:2905-10, 2009.