2015年度

Hassan WA, Yoshida R, Kameyama H, Kudoh S, Hasegawa K, Niimori-Kita K, Ito T.
Notch1 controls cell chemoresistance in small cell lung carcinoma cells.
Thoracic Cancer. First published: 29 July 2015　
DOI: 10.1111/1759-7714.12297View/save citation

Masatoshi Hirayama, Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yuya Imamura, Mohammad Abu Sayem, Atsushi Irie, Yoshihiro Yoshitake, Daiki Fukuma, Masanori Shinohara, Akinobu Hamada, Hirofumi Jono, Eiji Yuba, Kenji Kono, Koji Yoshida, Takuya Tsunoda, Hideki Nakayama and Yasuharu Nishimura
An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs
OncoImmunology in press

Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, and Yasuharu Nishimura Identification of Glypican-3-Derived Long Peptides Activating both CD8+ and CD4+ T-cells; Prolonged
Overall Survival in Cancer Patients with Th Cell Response
OncoImmunology. 5(1): e1062209-1-14 (2015)

Yoshihiro Yoshitake, Daiki Fukuma, Akira Yuno, Masatoshi Hirayama, Hideki Nakayama, Takuya, Tanaka, Masashi Nagata, Yasuo Takamune, Kenta Kawahara, Yoshihiro Nakagawa, Ryoji Yoshida, Akiyuki Hirosue, Hidenao Ogi, Akimitsu Hiraki, Hirofumi Jono, Akinobu Hamada, Koji Yoshida,
Yasuharu Nishimura, Yusuke Nakamura, and Masanori Shinohara
Clinical Cancer Research. 21(2): 312-21 (2015)

Hisaki Naito, Hidenobu Kamohara, Toshinori Oshima, Junji Yamashita, Kentaro Tokunaga, Daisuke Niimori, Atsushi Kotera, Katsuyuki Sagishima, Hideki Nakayama and Yoshihiro Kinoshita
Infective Endocarditis Caused by Odontogenic Infection with Dentinogenesis Imperfecta in Jeune Syndrome.
Journal of Clinical Case reports.2015,5:10 J Clin Case Rep 5(10):604.(2015)

Nishimura Y, Tomita Y, Yuno A, Yoshitake Y, Shinohara M. Cancer immunotherapy using novel tumor-associated antigenic peptides identified by genome-wide cDNA microarray analyses.
Cancer Science. 106:505-11 (2015)

Yoshitake Y, Fukuma D, Yuno A, Hirayama M, Nakayama H, Tanaka T, Nagata M, Takamune Y, Kawahara K, Nakagawa Y, Yoshida R, Hirosue A, Ogi H, Hiraki A, Jono H, Hamada A, Yoshida K, Nishimura Y, Nakamura Y, Shinohara, M.
Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
Clin. Cancer Res. 21:312-21 (2015)

Hirayama M, Tomita Y, Yuno A, Tsukamoto H, Senju S, Imamura Y, Mohammad Sayem, Irie A, Yoshitake Y, Fukuma D, Shinohara M, Hamada A, Jono H, Yuba E, Kono K, Yoshida K, Tsunoda T, Nakayama H, Nishimura Y. An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs. Oncoimmunology. 2015 in press.

Matsuoka Y, Yoshida R, Nakayama H, Nagata M, Hirosue A, Tanaka T, Kawahara K, Nakagawa Y, Sakata J, Arita H, Hiraki A, Shinohara M.
The tumour stromal features are associated with resistance to 5-FU-based chemoradiotherapy and a poor prognosis in patients with oral squamous cell carcinoma.
APMIS. 123(3):205-14 (2015)

Notch1 controls cell chemoresistance in small cell lung carcinoma cells.
Thoracic Cancer. First published: 29 July 2015
citation

Wei FY, Zhou B, Suzuki T, Miyata K, Ujihara Y, Horiguchi H, Takahashi N, Xie P, Michiue H, Fujimura A, Kaitsuka T, Matsui H, Koga Y, Mohri S, Suzuki T, Oike Y, and Tomizawa K.
Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans. Cell Metab. 21(3): 428-442. (2015)

Nakamura T, Shinriki S, Jono H, Guo J, Ueda M, Hayashi H, Yamashita S, Zijlstra A, Nakayama H, Hiraki A, Shinohara M, and Ando Y
Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells. Oncotarget. 6(2):1008-19(2015)

Nakamura T, Shinriki S, Jono H, Ueda M, Nagata M, Guo J, Hayashi H, Yoshida R, Ota T, Ota K, Kawahara K, Nakagawaa Y, Yamashita S, Nakayama H, Hiraki A, Shinohara M, and Ando Y
Osteopontin-integrin αvβ3 axis is crucial for 5-fluorouracil resistance in oral squamous cell carcinoma. FEBS Lett . 589(2):231-9(2015)